{"id":5727,"date":"2025-10-08T09:56:27","date_gmt":"2025-10-08T09:56:27","guid":{"rendered":"https:\/\/www.intnews.it\/?p=5727"},"modified":"2025-10-08T09:56:27","modified_gmt":"2025-10-08T09:56:27","slug":"nanophoria-record-funding-of-83-million","status":"publish","type":"post","link":"https:\/\/intnews.it\/en\/nanophoria-record-funding-of-83-million\/","title":{"rendered":"Nanophoria, record funding of 83 million to revolutionize cardiovascular therapies"},"content":{"rendered":"\n<div style=\"height:50px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p><strong><a href=\"https:\/\/www.nanophoria.com\/it\/home\/\" target=\"_blank\" rel=\"noreferrer noopener\">Nanophoria<\/a>, record funding of 83 million euros which represents an unprecedented injection of trust for the startup focused on cardiovascular therapies and for the entire Italian biotech sector.<\/strong><\/p>\n\n\n\n<div style=\"height:50px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>The transaction, which stands as the largest ever recorded for a biotech startup in Italy, was led by a consortium of leading investors:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Xgen Venture<\/strong><\/li>\n\n\n\n<li><strong>Sofinnova Partners<\/strong><\/li>\n\n\n\n<li><strong>Cdp Venture Capital<\/strong><\/li>\n\n\n\n<li><strong>Panakes Partners<\/strong><\/li>\n<\/ul>\n\n\n\n<p>This significant investment marks a fundamental milestone for the company and for the entire national life science innovation ecosystem.<\/p>\n\n\n\n<div style=\"height:50px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p class=\"has-medium-font-size\"><strong>An innovative technology for cardiovascular diseases<\/strong><\/p>\n\n\n\n<p>Nanophoria&#8217;s mission is ambitious: to redefine therapeutic paradigms for cardiovascular disease and other high-impact chronic conditions. The capital raised will be crucial to accelerate the development of <strong>NP-MP1<\/strong>, the company&#8217;s most advanced drug candidate, intended for the treatment of heart failure.<\/p>\n\n\n\n<p>The funds will support the preclinical studies needed to submit the Investigational New Drug (IND) application to the US FDA, an indispensable formal step in starting the human clinical trial.<\/p>\n\n\n\n<p>&#8220;This funding allows us to accelerate the clinical development of NP-MP1 and expand our pipeline,&#8221; said <strong>Claudio De Luca, CEO and co-founder of Nanophoria<\/strong>. &#8220;Our innovative delivery platform allows us to reach hitherto inaccessible cellular targets in cardiomyocytes, bringing us closer to the goal of offering life-changing therapies for patients.&#8221;.<\/p>\n\n\n\n<div style=\"height:50px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p class=\"has-medium-font-size\"><strong>NP-MP1: A New Hope for Heart Failure (HFrEF)<\/strong><\/p>\n\n\n\n<p>The drug NP-MP1 is based on proprietary &#8220;<strong>nano-in-micro<\/strong>&#8221; technology, which allows biological drugs to be administered directly to the heart through inhalation. This non-viral approach has demonstrated excellent efficacy in preclinical models of heart failure with reduced ejection fraction (HFrEF).<\/p>\n\n\n\n<p>HFrEF is a debilitating disease that affects millions of people worldwide, with a five-year mortality rate of approximately 40%. Nanophoria therapy aims to intervene directly on one of the underlying causes of the disease, improving cardiac contractility.<\/p>\n\n\n\n<div style=\"height:50px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p class=\"has-medium-font-size\"><strong>Investor confidence in Italian biotech<\/strong><\/p>\n\n\n\n<p>The success of this funding round testifies to the scientific validity of the Nanophoria project and the attractiveness of the Italian biotech sector.<\/p>\n\n\n\n<p><strong>Paolo Fundar\u00f2, managing partner at Xgen Venture<\/strong>, commented: &#8220;The science of NanoPhoria offers a new and concrete approach to delivering highly potent therapies directly to the heart. We are excited to partner with a consortium of top-tier investors to support a company that responds to real medical needs.\u201d.<\/p>\n\n\n\n<p>With this capital, Nanophoria Bioscience is now positioned to accelerate its research and bring new hope to millions of patients around the world.<\/p>\n\n\n\n<div style=\"height:50px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p class=\"has-small-font-size\"><em>More content like this: <a href=\"https:\/\/www.intnews.it\/categorie\/economia\/\">Link<\/a> <\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Nanophoria Bioscience closes an 83 million Serie A round, the largest for a biotech startup in Italy. Discover innovative technology to treat heart failure and chronic diseases.<\/p>\n","protected":false},"author":6,"featured_media":5723,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"categories":[148],"tags":[127],"class_list":{"0":"post-5727","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-economy","8":"tag-sustainability"},"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Nanophoria, record funding of 83 million to revolutionize cardiovascular therapies - INT News Nanophoria record financing of 83 million<\/title>\n<meta name=\"description\" content=\"Nanophoria Bioscience closes an 83 million Serie A round, the largest for a biotech startup in Italy. 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